goat anti ve cadherin  (Santa Cruz Biotechnology)

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

Article Title: Curative effects and mechanisms of AG1296 and LY294002 co-therapy in Angiostrongylus cantonensis-induced neurovascular unit dysfunction and eosinophilic meningoencephalitis.

doi: 10.1016/j.jmii.2024.05.012

Figure Lengend Snippet: Figure 7. Degradation of collagen type IV and fibronectin. The degradation of collagen type IV (a) and fibronectin (c) was analyzed in the brains of wild-type, AG1296 (AG)-treated, LY294002 (LY)-treated, AG þ LY co-treated, and matrix metalloproteinase-9 (MMP-9) knockout (KO) mice using Western blot analysis during Angiostrongylus cantonensis infection. Quantification and normalization of collagen type IV (b) and fibronectin (d) to b-actin were performed with a computer-assisted imaging densitometer system. *indicates a statistically significant increase in A. cantonensis-infected mice compared with the control. # indicates a statistically significant decrease in AG1296 (AG) alone, LY294002 (LY) alone, AG þ LY co-therapy, or MMP-9 knockout (KO) mice compared with A. cantonensis-infected mice.

Article Snippet: The goat anti-mouse phosphorylated polyclonal antibody PI3K (p-PI3K), the goat anti-mouse phosphorylated Akt (pAkt) polyclonal antibody, the goat anti-mouse collagen type IV polyclonal antibody and goat anti-mouse fibronectin polyclonal antibody were purchased from Santa Cruz Biotechnology (CA, USA).

Techniques: Knock-Out, Western Blot, Infection, Imaging, Control